Pfm Health Sciences, L.P. 13F annual report
Pfm Health Sciences, L.P. is an investment fund managing more than $2.27 trillion ran by Darin Sadow. There are currently 75 companies in Mrs. Sadow’s portfolio. The largest investments include Horizon Therapeutics Pub L and Cytokinetics Inc, together worth $234 billion.
$2.27 trillion Assets Under Management (AUM)
As of 7th February 2023, Pfm Health Sciences, L.P.’s top holding is 1,091,840 shares of Horizon Therapeutics Pub L currently worth over $124 billion and making up 5.5% of the portfolio value.
In addition, the fund holds 2,399,545 shares of Cytokinetics Inc worth $110 billion, whose value fell approximately 0.1% in the past six months.
The third-largest holding is Lilly Eli & Co worth $109 billion and the next is Centene worth $91.2 billion, with 1,112,480 shares owned.
Currently, Pfm Health Sciences, L.P.'s portfolio is worth at least $2.27 trillion. The total portfolio value may be much higher due to cash
assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.
Careers at Pfm Health Sciences, L.P.
The Pfm Health Sciences, L.P. office and employees reside in San Francisco, California. According to the last 13-F report filed with the SEC, Darin Sadow serves as the General Counsel and Chief Compliance Officer at Pfm Health Sciences, L.P..
Recent trades
In the most recent 13F filing, Pfm Health Sciences, L.P. revealed that it had opened a new position in
Biogen Inc and bought 155,659 shares worth $43.1 billion.
This means they effectively own approximately 0.1% of the company.
Biogen Inc makes up
2.6%
of the fund's Health Care sector allocation and has grown its share price by 35.7% in the past year.
The investment fund also strengthened its position in Penumbra Inc by buying
177,244 additional shares.
This makes their stake in Penumbra Inc total 360,030 shares worth $80.1 billion.
Penumbra Inc soared 20.6% in the past year.
On the other hand, there are companies that Pfm Health Sciences, L.P. is getting rid of from its portfolio.
Pfm Health Sciences, L.P. closed its position in Jazz Pharmaceuticals plc on 14th February 2023.
It sold the previously owned 571,936 shares for $89.2 million.
Darin Sadow also disclosed a decreased stake in Cytokinetics Inc by approximately 0.1%.
This leaves the value of the investment at $110 billion and 2,399,545 shares.
One of the largest hedge funds
The two most similar investment funds to Pfm Health Sciences, L.P. are Periscope Capital and Cramer Rosenthal Mcglynn. They manage $2.26 trillion and $2.27 trillion respectively.
Darin Sadow investment strategy
Pfm Health Sciences, L.P.’s portfolio is diversified across 3 sectors.
Currently, their heaviest sector is Health Care — making up 72.1% of
the total portfolio value.
The fund focuses on investments in the United States as
62.7% of the portfolio companies
are based in the United States.
The majority of the companies in the fund’s portfolio are large-cap stocks.
Stocks with a size of more than $10 billion in market cap make up
33% of the total holdings value.
On the other hand, small-cap stocks make up only 1.3% of the portfolio.
The average market cap of the portfolio companies is close to $54.8 billion.
The complete list of Pfm Health Sciences, L.P. trades based on 13F SEC filings
These positions were updated on February 14th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.
| Security | Shares Owned | Value | Allocation |
|---|---|---|---|
| Horizon Therapeutics Pub L |
No change
1,091,840
|
$124,251,392,000 | 5.48% |
| Cytokinetics Inc |
2.66%
2,399,545
|
$109,947,152,000 | 4.85% |
| Lilly Eli & Co |
No change
298,643
|
$109,255,555,000 | 4.82% |
| Centene Corp. |
No change
1,112,480
|
$91,234,485,000 | 4.03% |
| Humana Inc. |
No change
166,066
|
$85,057,345,000 | 3.75% |
| Axsome Therapeutics Inc |
19.68%
1,092,831
|
$84,290,055,000 | 3.72% |
| Penumbra Inc |
96.97%
360,030
|
$80,092,274,000 | 3.53% |
| Unitedhealth Group Inc |
4.05%
116,067
|
$61,536,402,000 | 2.71% |
| Arcus Biosciences Inc |
19.22%
2,703,287
|
$55,903,975,000 | 2.47% |
| Abbvie Inc |
33.75%
329,344
|
$53,225,284,000 | 2.35% |
| Prothena Corp Plc |
153.67%
875,464
|
$52,746,706,000 | 2.33% |
| Uniqure Nv |
2.95%
2,302,314
|
$52,193,458,000 | 2.30% |
| Cardinal Health, Inc. |
No change
639,783
|
$49,180,119,000 | 2.17% |
| Molina Healthcare Inc |
No change
143,779
|
$47,478,701,000 | 2.09% |
| IQVIA Holdings Inc |
3.33%
229,081
|
$46,936,406,000 | 2.07% |
| Cigna Corp. |
No change
141,300
|
$46,818,342,000 | 2.07% |
| Danaher Corp. |
No change
175,690
|
$46,631,640,000 | 2.06% |
| iRhythm Technologies Inc |
No change
493,721
|
$46,246,846,000 | 2.04% |
| Syndax Pharmaceuticals Inc |
212.45%
1,814,634
|
$46,182,435,000 | 2.04% |
| Biogen Inc |
Opened
155,659
|
$43,105,090,000 | 1.90% |
| Merck & Co Inc |
62.18%
367,634
|
$40,788,992,000 | 1.80% |
| Dynavax Technologies Corp. |
No change
3,805,370
|
$40,489,137,000 | 1.79% |
| Mckesson Corporation |
No change
105,811
|
$39,691,822,000 | 1.75% |
| Argenx Se |
No change
104,732
|
$39,675,624,000 | 1.75% |
| Edwards Lifesciences Corp |
56.74%
530,030
|
$39,545,538,000 | 1.74% |
| Astrazeneca plc |
No change
576,800
|
$39,107,040,000 | 1.73% |
| Elevance Health Inc |
57.05%
67,115
|
$34,427,982,000 | 1.52% |
| Thermo Fisher Scientific Inc. |
No change
62,143
|
$34,221,529,000 | 1.51% |
| Avantor, Inc. |
22.70%
1,607,612
|
$33,904,537,000 | 1.50% |
| Point Biopharma Global Inc |
Opened
4,633,802
|
$33,780,417,000 | 1.49% |
| Waters Corp. |
19.56%
94,624
|
$32,416,290,000 | 1.43% |
| Biomarin Pharmaceutical Inc. |
63.02%
310,401
|
$32,123,399,000 | 1.42% |
| Intuitive Surgical Inc |
Opened
114,450
|
$30,369,308,000 | 1.34% |
| Caribou Biosciences Inc |
25.67%
4,459,783
|
$28,007,437,000 | 1.24% |
| Agilent Technologies Inc. |
Opened
183,504
|
$27,461,374,000 | 1.21% |
| Karuna Therapeutics Inc |
No change
130,293
|
$25,602,575,000 | 1.13% |
| Biocryst Pharmaceuticals Inc. |
No change
2,162,411
|
$24,824,478,000 | 1.10% |
| Seagen Inc |
31.87%
192,384
|
$24,723,268,000 | 1.09% |
| Johnson & Johnson |
77.60%
137,746
|
$24,332,831,000 | 1.07% |
| HCA Healthcare Inc |
Opened
91,945
|
$22,063,122,000 | 0.97% |
| Procept Biorobotics Corp |
44.77%
517,526
|
$21,498,030,000 | 0.95% |
| Erasca Inc |
18.43%
4,797,460
|
$20,677,053,000 | 0.91% |
| IVERIC bio Inc |
1.27%
917,557
|
$19,644,895,000 | 0.87% |
| Arcellx Inc |
Opened
616,515
|
$19,099,635,000 | 0.84% |
| Universal Hlth Svcs Inc |
60.80%
124,421
|
$17,529,675,000 | 0.77% |
| Apellis Pharmaceuticals Inc |
Opened
318,422
|
$16,465,602,000 | 0.73% |
| Icon Plc |
48.34%
81,725
|
$15,875,081,000 | 0.70% |
| Charles Riv Labs Intl Inc |
Opened
72,820
|
$15,867,478,000 | 0.70% |
| Dexcom Inc |
Opened
135,465
|
$15,340,057,000 | 0.68% |
| Editas Medicine Inc |
132.93%
1,466,732
|
$13,009,913,000 | 0.57% |
| Tenet Healthcare Corp. |
53.26%
254,525
|
$12,418,275,000 | 0.55% |
| Pulmonx Corp |
Opened
1,455,770
|
$12,272,141,000 | 0.54% |
| Oak Str Health Inc |
8.65%
565,239
|
$12,158,291,000 | 0.54% |
| Generation Bio Co. |
4.68%
2,903,192
|
$11,409,545,000 | 0.50% |
| Celcuity Inc |
Opened
712,111
|
$9,976,675,000 | 0.44% |
| Essa Pharma Inc |
299.74%
3,844,332
|
$9,687,717,000 | 0.43% |
| Adaptimmune Therapeutics Plc |
46.83%
4,843,510
|
$7,071,525,000 | 0.31% |
| Praxis Precision Medicines I |
15.77%
2,777,467
|
$6,610,371,000 | 0.29% |
| Blueprint Medicines Corp |
Opened
130,366
|
$5,711,334,000 | 0.25% |
| Verve Therapeutics Inc |
74.29%
217,302
|
$4,204,794,000 | 0.19% |
| COMPASS Pathways plc |
29.75%
509,625
|
$4,092,289,000 | 0.18% |
| Laboratory Corp Amer Hldgs |
Opened
13,561
|
$3,193,344,000 | 0.14% |
| Pmv Pharmaceuticals Inc |
72.51%
333,716
|
$2,903,329,000 | 0.13% |
| Werewolf Therapeutics Inc |
25.27%
1,293,293
|
$2,651,251,000 | 0.12% |
| Bluebird bio Inc |
Opened
244,867
|
$1,694,480,000 | 0.07% |
| iTeos Therapeutics, Inc. |
86.82%
70,922
|
$1,385,107,000 | 0.06% |
| Io Biotech Inc |
76.49%
507,640
|
$1,167,572,000 | 0.05% |
| Keros Therapeutics, Inc. |
Opened
15,999
|
$768,272,000 | 0.03% |
| Xenon Pharmaceuticals Inc |
Opened
17,488
|
$689,552,000 | 0.03% |
| Bellus Health Inc |
Opened
63,864
|
$524,962,000 | 0.02% |
| Jounce Therapeutics Inc |
91.24%
345,926
|
$383,978,000 | 0.02% |
| Sana Biotechnology Inc |
93.41%
62,776
|
$247,965,000 | 0.01% |
| Vectivbio Hldg Ag |
Opened
25,541
|
$221,313,000 | 0.01% |
| Biohaven Ltd |
Opened
10,988
|
$152,513,000 | 0.01% |
| Jazz Pharmaceuticals plc |
Closed
571,936
|
$89,228,000 | |
| Iovance Biotherapeutics Inc |
Opened
13,337
|
$85,223,000 | 0.00% |
| Pfizer Inc. |
Closed
1,343,384
|
$70,434,000 | |
| Veeva Sys Inc |
Closed
202,387
|
$40,081,000 | |
| Icu Med Inc |
Closed
242,185
|
$39,813,000 | |
| Becton Dickinson & Co |
Closed
130,697
|
$32,221,000 | |
| Nevro Corp |
Closed
659,410
|
$28,902,000 | |
| Catalent Inc. |
Closed
218,366
|
$23,428,000 | |
| Myriad Genetics, Inc. |
Closed
1,177,250
|
$21,391,000 | |
| Baxter International Inc. |
Closed
323,907
|
$20,805,000 | |
| Intellia Therapeutics Inc |
Closed
163,280
|
$8,451,000 | |
| Sight Sciences Inc |
Closed
776,281
|
$6,979,000 | |
| Sophia Genetics Sa |
Closed
1,766,062
|
$6,393,000 | |
| Acadia Pharmaceuticals Inc |
Closed
384,995
|
$5,425,000 | |
| Aerie Pharmaceuticals Inc |
Closed
699,531
|
$5,246,000 | |
| Bcls Acquisition Corp |
Closed
464,103
|
$4,595,000 | |
| Jiya Acquisition Corp |
Closed
464,103
|
$4,585,000 | |
| Pardes Biosciences Inc |
Closed
801,204
|
$2,460,000 | |
| No transactions found | |||
| Showing first 500 out of 92 holdings | |||
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